男孩托马斯（迪伦·欧布莱恩 Dylan O'Brien 饰）在电梯中醒来，奇怪的是他除了名字之外什么都记不得。当电梯打开，他来到了一个陌生的地方“林间空地”。这里四周被高大的石头墙包围着，墙内住着许多男孩，有纽特（托马斯·桑斯特 Thomas Sangster 饰）、查克（布雷克·库珀 Blake Cooper 饰）、米诺（李基弘 Ki Hong Lee 饰）等人，他们都被困在迷宫里，而墙外还有一群巨大的怪兽威胁着。一天，电梯为他们送来了一个女孩特雷莎（卡雅·斯考达里奥 Kaya Scodelario 饰），她是来这里的第一个女孩。此后，迷宫逐渐开始发生变化，一切都陷入了混乱中，托马斯和特雷莎决定一起走上破解迷宫之路，找出迷宫背后令人不寒而栗的秘密。
影片改编自詹姆斯·达什纳撰写的同名反乌托邦科幻小说三部曲的第一本

After surviving an IED explosion in combat overseas, a young soldier with the Army Motorcycle Unit is medically discharged with a broken back and leg. Against all odds he trains to make an impossible comeback as a motocross racer in order to support his family.

在未来世界，军事情报分析师Atlas Shepherd（詹妮弗·洛佩兹 Jennifer Lopez 饰），对AI有着深切的不信任感。她加入了一个任务，试图捕捉一个叛逃的机器人，而这个机器人有着神秘的过去。不过，当计划失败时，她唯一拯救人类未来免受AI侵害的希望就是去相信它。

After joining the Military following the death of his mother, Jake Williams returns home from war to his Father, Paul, and his sister, Brittney. Shortly after making amends with his father, Paul, for leaving them, Jake is left with the struggle of taking care of his sister and his fathers multi-million dollar company after Paul is killed in a car accident. After a mobster named Joe gets information of Jake's situation, Joe kidnaps Brittney and holds her for a ransom. Jake decides to take it into his own hands to save his sister, but will he stop Joe from fulfilling his evil plan...

两名科学家试图阻止一种突变，这种突变在前一年被超级月亮触摸后将人变成狼人。